- Poster presentation
- Open access
- Published:
International validation of the delirium prediction model for ICU patients (PREDELIRIC): a multicenter observational study
Critical Care volume 17, Article number: P398 (2013)
Introduction
Delirium is a serious and frequent disorder in ICU patients. The aim of this study was to internationally validate the existing Prediction of Delirium ICU (PREDELIRIC) model to predict delirium in ICU patients.
Methods
A prospective multicenter cohort study was performed in eight ICUs in six countries (Table 1). The 10 predictors (age, APACHE II score, urgent and admission category, infection, coma, sedation, morphine use, urea level, metabolic acidosis) were collected within 24 hours after ICU admission. CAM-ICU was used to identify ICU delirium.
Results
A total of 2,852 adult ICU patients were screened and 1,824 (64%) were included. Main exclusion reasons were length of stay <1 day (19.1%) and sustained coma (4.1%). Mean ± CAM-ICU compliance was 82 ± 16% and inter-rater reliability 0.87 ± 0.17. Overall delirium incidence was 19.9% (range 27.2%). Despite significant differences between centres on all 10 predictors, the overall area under the receiver operating characteristic curve (AUROC) of the eight centers was 0.77 (95% CI: 0.74 to 0.79).
Conclusion
The overall predictive value of the PREDELIRIC model was good, indicating that the prediction model can now be used internationally.
Author information
Authors and Affiliations
Rights and permissions
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
About this article
Cite this article
van den Boogaard, M., Schoonhoven, L., Maseda, E. et al. International validation of the delirium prediction model for ICU patients (PREDELIRIC): a multicenter observational study. Crit Care 17 (Suppl 2), P398 (2013). https://doi.org/10.1186/cc12336
Published:
DOI: https://doi.org/10.1186/cc12336