Tissue hypoxia during acute hemorrhage
Division of Pulmonary and Critical Care Medicine, Penn State University College of Medicine, Penn State Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
Critical Care 2013, 17:423 doi:10.1186/cc12519
See related commentary by Calzia et al., http://ccforum.com/content/16/6/183Published: 28 March 2013
First paragraph (this article has no abstract)
Calzia and colleagues argue  that tissue hypoxia in a rat model of hemorrhage that led to an oxygen deficit of 120 ml/kg with hyperlactacidemia  may be modest, and may not affect hydrogen sulfide oxidation since '... the arterial oxygen partial pressure was still normal ...' . This contention requires clarification.