Email updates

Keep up to date with the latest news and content from Critical Care and BioMed Central.

Highly Accessed Open Badges Commentary

Good and bad fever

Jean-Marc Cavaillon

Author Affiliations

Unit of Cytokines & Inflammation, Department of Infection and Epidemiology, Institut Pasteur, 28 rue Dr Roux, F-75015 Paris, France

Critical Care 2012, 16:119  doi:10.1186/cc11237

See related research by Egi et al.,

Published: 20 March 2012


Fever is considered a key actor of innate immunity aimed to fight infection. A new investigation reports an association of the use of antipyretic drugs with poorer outcome among patients with sepsis. In contrast, high temperature in non-infectious intensive care patients is associated with higher mortality.