http://ccforum.com/content/11/5/314/comments The latest comments on the article 'Albumin and furosemide for acute lung injury' 2007-10-08T09:56:35Z http://ccforum.com/content/11/5/314/comments#285652 <p>I think that the median Apache score of the study population was about 15. In a population with a greater severity of illness we might expect the level of inflammation and therefore endothelial dysfunction to be greater. It is possible that if that were the case the albumin may leak out of the vascular compartment and not provide the same increase in oncotic pressure. The benefits of such a therapy may then be lost. However the concept of increasing oncotic pressure and simultaneous diuresis for ALI/ARDS is certainly appealing.</p> Shahed Omar 2007-10-08T09:56:35Z http://ccforum.com/content/11/5/314 Khan et al. Critical Care 11 314 Thu Sep 27 00:00:00 BST 2007