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Open Badges Commentary

Tight glucose control: should we move from intensive insulin therapy alone to modulation of insulin and nutritional inputs?

Pierre Kalfon1* and Jean-Charles Preiser2

Author Affiliations

1 Department of General Intensive Care, Hospital of Chartres, 34, rue du Docteur Maunoury, 28000 Chartres, France

2 Department of Intensive Care, University Hospital of Liege, Domaine du Sart Tilman B 35, B-4000 Liege 1, Belgium

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Critical Care 2008, 12:156  doi:10.1186/cc6915

See related research by Chase et al.,

Published: 19 June 2008


The report by Chase and coworkers in the previous issue of Critical Care describes the implementation into clinical practice of the Specialized Relative Insulin Nutrition Table (SPRINT) for tight glycaemic control in critically ill patients. SPRINT is a simple, wheel-based system that modulates both insulin rate and nutritional inputs. It achieved a better glycaemic control in a severely ill critical cohort than their previous method for glycaemic control in a matched historical cohort. Reductions in mortality were also observed.